Pardon my skepticism, but I have posted at least a dozen of these announcements before.
If this one is legit and it is effective, there will be serious doubts that it will be allowed to be put into use. Why do I say that? I say it because the fucking Pharmaceutical companies would not be getting such a hefty profit from their HIV overpriced drugs.
The billions of dollars of revenue that these drug manufacturers get from HIV, cancer and other life-saving drugs is staggering. If they don’t find a way of blocking and preventing it from going to market they stand to lose all that obscene profit.
"Functional HIV Cure" Trial Advances
Sangamo BioSciences, Inc. (Nasdaq: SGMO) announced today the initiation of two new Phase 2 clinical studies (SB-728-1101 and SB-728-902, Cohort 5) in its program to develop a "functional cure" for HIV/AIDS. Sangamo's ZFP Therapeutic® approach (SB-728-T) generates T-cells that are resistant to HIV infection using its zinc finger nuclease (ZFN) technology to permanently disrupt the DNA sequence encoding CCR5, a co-receptor used by HIV to enter cells. The company expects to present data from its SB-728-T HIV clinical trials at appropriate medical meetings in 2012.
Most interesting: "In addition to safety, the study will evaluate the effect of escalating doses of Cytoxan on SB-728-T engraftment, the effect of SB-728-T treatment on viral load following HAART interruption." In other words (I think), they'll be looking at whether patients can cease taking meds after the treatment.
Our thanks for bringing this post to us and for a great blog.
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